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doi: 10.1007/s00702-020-02288-7 84 GuerreroJGaticaHARodrguezMEstayRGoeckeI

When semaglutide, tirzepatide, and other GLP-1 receptor agonists cause fluid and electrolyte losses through gastrointestinal side effects, or when reduced food intake limits your natural electrolyte consumption and/or water intake via food, your gut function can suffer

There is also a clear association with primary and secondary Sjogren's syndrome(48)

Use of GLP-1 agonists compared with bupropion-naltrexone was associated with increased risk of pancreatitis (adjusted HR, 9.09 [95% CI, 1.25-66.00]), bowel obstruction (HR, 4.22 [95% CI, 1.02-17.40]), and gastroparesis (HR, 3.67 [95% CI, 1.15-11.90) but not biliary disease (HR, 1.50 [95% CI, 0.89-2.53])

occasional mild injectionsite reactions (redness, tenderness) reported