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the disulfide bond is sensitive to strongly reducing conditions
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A continuous exposure might be necessary for chronic studies, whereas acute investigations might only require a single dose
The pancreatic secretion of intrinsic factor is reduced or absent, secondary dysbiosis of the intestine is common, and the mucosa may be compromised by the presence of excessive bacterial numbers and toxic metabolites
Concurrent iron-deficiency anemia and folic acid deficiency may result in a blunted or impeded response to cyanocobalamin therapy.1
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