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However, the studies included were of shorter duration (three months) with a limited number of patients and wide confidence intervals [35]

In the CNS it induces hypothalamic gliosis and lipid accumulation, which may disrupt appetite and energy regulation [67]

IgE versus IgG4 production can be differentially regulated by IL-10

Reactive oxygen species (ROS), in excess, can cause disruption to normal cellular function and can damage cells (in particular mitochondria, & DNA of the sperm and egg) and tissues