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Why might this association exist

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When PD-L1 attaches to PD-1 on T cells, it significantly reduces subsequent signaling pathways like PI3K/Akt/mTOR and Ras/MEK/ERK, usually initiated by CD28 activation, resulting in the inhibition of T-cell metabolism and the triggering of T-cell cycle arrest [101, 102]

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Read the terms and conditions, then check the box to submit an electronic signature

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Regulatory Statement: The information presented in case studies have been de-identified in accordance with the HIPAA Privacy protection

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