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One recent study in patients with psoriasis and psoriatic arthritis found that overweight individuals who combined a GLP-1 agonist with an anti-IL-17 medication experienced both weight loss and improved disease control compared to those using immunosuppressive therapy alone

Critically, nausea frequency and severity typically decrease over time as the body adapts to GLP-1 receptor activation

As these fibers mature over the following weeks and months, the skin gradually firms and retracts alongside the changing body composition

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At baseline, mean HbA 1c and body weight were 63 mmol/mol (8.0%) and 79.6 kg, respectively