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AACR Annual Meeting 2015, 2015

GPX4 catalyzes the reduction of hydrogen peroxide, organic hydroperoxides, and lipid peroxides at the expense of reduced glutathione and functions in the protection of cells against oxidative stress

Rojas D, Abad C, Proverbio T, Piero S, Pia M, Proverbio F, Marn R (2025) Bridging models: preeclampsia biomarkers in salt-loaded rats and human patients

Peroxyl radicals (RO) RO are an important class of ROS primarily generated within cells through lipid peroxidation chain reactions, particularly in the regions rich in unsaturated fatty acids located in cell membranes [62]

A large body of preclinical data suggesting a cardioprotective effect of NAC in diabetes was highlighted, most likely related to the ability of NAC to reduce oxidative stress