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doi: 10.1038/cdd.2015.93 56 BannaiSKitamuraE

This means it affects the levels of certain chemicals in the brain

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However, evidence from research studies suggests that GLP-1 analogs may also reduce gastric acid secretion, which can impair the conversion of dietary B12 into its absorbable form and decrease binding to intrinsic factor, both of which are necessary for proper absorption

The studies showed that survodutide therapy led to a maximum placebo-corrected body weight loss of 13.8% by week 16, demonstrating its potential for significant weight loss [110]