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Chemically, they consist of benzene rings with OH moieties and range from the simpler ones like phenolic acids, to structurally complicated ones such as tannins (Khan et al

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Figure 4 8 Translational outlook: analogs, safety liabilities, and delivery strategies Erastin has demonstrated antitumor activity in several malignancies, including gastric and colorectal cancer (69, 70), and the inflammatory, iron-loaded, oxidative microenvironment shared by many tumors and EMS provides a coherent theoretical basis for applying this strategy to EMS (71, 72)