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Endogenous glucose-dependent insulinotropic polypeptide contributes to sitagliptin-mediated improvement in -cell function in patients with type 2 diabetes

It also suppresses glucagon secretion, slows gastric emptying, reduces food intake, and promotes beta-cell proliferation

Quantitation was performed with 1,3,5-tribromobenzene as the internal standard and the D 1 NMR acquisition delay parameter in Topspin was set to 10 s to ensure accurate NMR integrations

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Research has focused on inflammatory pathway modulation, particularly in gut tissue and skin inflammation models