At week 12, there were no significant differences found between the treatment and placebo groups in terms of the total number of UV spots, spot polarization, or measurements of skin tone
In contrast, those using Tirzepatide achieved higher monthly weight loss percentages: approximately 5.9% after 3 months, 10.1% after 6 months, and 15.3% after 12 months, surpassing the weight loss observed with semaglutide
This results in effects secondary to both GLP-1 and GIP receptor activation, such as increased beta cell function and inhibition of glucagon secretion [35]
More importantly, compared with FTY270 approved by the FDA for the treatment of chronic MS, ORY-2001 does not target 1R, does not have bradycardia, and does not cause gastrointestinal toxicity [195]
Avoid heat and direct sunlight