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Older adults and anti-aging goals NR shows remarkable potential for age-related issues

Heres how the evidence stacks up when we look at effectiveness by goal: Cognitive performance: Citicoline and alpha-glycerophosphocholine (alpha-GPC) are choline compounds that appear to cross the bloodbrain barrier and support acetylcholine, which is critical for brain function.4 5 6 Citicoline has the strongest trial evidence at 250-500mg/day, while alpha-GPC shows promise but with fewer studies.7 8 Athletic performance: Small preliminary trials suggest alpha-GPC may enhance lower-body power at 600mg/day and support post-exercise recovery at 1,000mg/day.9 10 Liver health: Phosphatidylcholine (PC) is a common supplemental form of choline that helps package and export fats from the liver

Accessed July 11, 2025

Your deficiency is moderate to severe, causing significant symptoms like anemia or neurological problems

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