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For complete folding and serine protease activity NS3 requires the intercalation of a -strand present in NS4A (refs 2123)

Using a new, sterile needle for each injection, rotating anatomical sites systematically, and allowing skin antiseptic to dry before needle insertion reduce localized irritation and infection risk

Marks, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Rosacea can flare throughout an individuals lifetime