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Even medically supervised diets and older classes of weight loss medications have failed to help people achieve and sustain their desired weights, keeping people locked in the never-ending cycle of weight loss and regain

The researchers concluded that long-term body mass loss is only partially mediated by caloric restriction melanocortin system activation appears to increase energy expenditure independently (Cote et al., 2017)

If youre not sure, your GP (or a private blood test provider) can help you check B12 alongside other useful markers