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Phase 3 data (TRIUMPH-4) showed average weight loss of 28.7% body weight at the 12mg dose over 68 weeks, equivalent to approximately 71.2 pounds from an average starting weight of 248.5 pounds

SKOV3 and OVCA429 cells were sensitive to erastin-induced cell death (Fig

Most meaningful BMI changes occur when treatment lasts at least 1216 weeks, with the most significant improvements seen over 612 months

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