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Common side effects during the adjustment period (typically the first 24 weeks): Mild nausea usually less intense than when first starting a GLP-1 medication Changes in appetite (some patients notice less appetite suppression early on at the starting 0.25 mg dose) Mild stomach discomfort, bloating, or constipation Injection site reactions Side effects that are less likely during the switch (compared to first-time GLP-1 use), but still possible: Significant vomiting less common given prior GLP-1 exposure, but possible Hypoglycemia particularly relevant for type 2 diabetes patients on insulin or sulfonylureas

As mentioned above, Wegovy can stay at room temperature for up to 28 days

These tumors have not been reported in humans, but rodent studies have shown evidence of thyroid tumors, including thyroid cancer

Food and Drug Administration for chronic weight management in combination with a low-calorie diet and increased physical activity