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10.1186/s12951-023-02250-1 71

In older adults, this often goes unnoticed until something acute happens

This cellular energy crisis is what causes the debilitating crashes and profound physical exhaustion experienced by patients after even minor physical or cognitive exertion, highlighting the critical need for antioxidant restoration

In the present review, we provide a systematic summary of the current progress in development of transporter-utilizing (pro)drugs and nanocarriers for delivery of drugs to the brain