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Third, because patients may have highly variable courses with or without treatment, findings from studies that have small sample sizes even well-designed studies potentially lack generalizability because of the inherent instability of findings derived from small numbers of patients

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Depletion of GSH with the GCL inhibitor BSO leads to gliosis and neuroinflammation in the rat brain, with a particular increase in levels of TNF (Gonzlez-Fraguela et al., 2018)

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Neuropsychopharmacology 25 (2), 165172