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10.1254/jphs.11R08CP 57

Diverse targets of SMN2-directed splicing-modulating small molecule therapeutics for spinal muscular atrophy

Matt Kaeberlein, the Chief Executive Officer of Optus Span Inc., an affiliate professor at the University of Washington, and a co-founder of the Dog Aging Project

Additional investigation reveals that estrogen diminishes the capacity of auranofin to elicit IL-6/hepcidin signal in Huh7 cells, offering a molecular rationale for auranofin's ineffectiveness in female Hfe/ mice

The approval of Exxuawhich Houstonbased Fabre-Kramer states is the first and only approved antidepressant for adults with MDD that works through the selective agonism of 5HT1a receptors to modulate serotonin throughout the central nervous systemwas hard won