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High-fat, fried, and very rich foods are the most common triggers for nausea and gastrointestinal discomfort on GLP-1 medications because they slow gastric emptying further on top of the medication's effect

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Neuroscience and Behavioral Physiology, 26 (6), 567-571

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Since the response is dose-sensitive and even biphasic, careful studies test a spread of concentrations across several orders of magnitude rather than betting on one number

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