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Signs of toxicity, such as alopecia and dermatitis, have been seen following an intake of 300 g/day over a long period and may result in unexpectedly increased mortality after 5 years [21]

At higher inhibitor concentrations, the curves were not hyperbolic, but became polynomial, suggesting that more than one binding site of OPZ is involved in the presence of reacted and unreacted enzymes species in mixture

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[7] By inhibiting Caspase-3, Epithalon might contribute to cellular longevity and reduced apoptosis, which may complement its regenerative potential, yet this hypothesis demands more comprehensive research for validation

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