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Additional downstream mediators include ErbB ligands such as epiregulin and vasoactive intestinal polypeptide (VIP) (68)
The enhanced antitumor activity to BxPC-3 cells should be attributed to the enhanced drug cellular uptake mediated by ORI@CPD-Lipo nanoparticles, chemical toxicity of the released ORI from the nanoparticles
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These polysaccharides contribute to maintaining the integrity of the intestinal barrier by increasing tight junction proteins (TJP) and modulating the production of SCFAs by the gut microbiota
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