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As anticipated, ALC prevented the alcohol-elicited loss of LTP and LFS synaptic transmission in the frontal cortex, suggesting that ALC blocked the loss of neuronal activity, perhaps by stabilizing mitochondrial function

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277,278 TLR signaling pathway TLRs are a class of receptor proteins that play a key role in the immune system by recognizing foreign pathogens such as bacteria and viruses through specific molecular patterns that trigger immune responses

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GLP-1 boosts insulin secretion from pancreatic beta cells in a glucose-dependent manner (meaning it only works when blood glucose is elevated, reducing hypoglycemia risk), suppresses glucagon secretion from pancreatic alpha cells (reducing glucose production by the liver), slows gastric emptying (prolonging satiety and reducing postprandial glucose spikes), and starts GLP-1 receptors in the brain (very the hypothalamus) to reduce appetite and food intake

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