However, research into how it affects athletic performance is limited and different fitness levels, age and gender play an important role too
GLP-1 is an FDA approved prescription medication that has been shown to result in up to 15% weight reduction (or more in some individuals)
"The potential use of coenzyme Q10 supplements alone or in combination with other drug therapies and nutritional supplements may help prevent or treat some of the following conditions: cardiovascular diseases, high blood pressure, cancer, periodontal diseases, mitochondrial disorders, radiation injury, obesity, diabetes, Parkinson's disease, acquired immune deficiency syndrome (AIDS), gastric ulcers, allergy, migraine headaches, kidney failure, muscular dystrophy, and aging."
What they found (summary): Development of Melanotan II as a cutaneous drug failed due to the combination of side effects Bifurcation into more selective derivatives was both scientifically and commercially successful PT-141 Bremelanotide (Vyleesi, 2019) Melanotan I Afamelanotide (Scenesse, 2014) Underground use of Melanotan II is safety-problematic Why it matters: This is the definitive historical review by the founders of the field
[1] Clinical trials for Wegovy, including the STEP programme (Semaglutide Treatment Effect in People with obesity), have primarily focused on weight loss efficacy and cardiometabolic outcomes