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doi: 10.1007/s12035-017-0550-2

The simple reduction of hydrogen bonding potential by altering polar side groups has successfully increased permeability of the BBB to some small peptides

on the expression of genes and proteins like TLR4 and PTGS2, and compare the outcomes of groups treated with and without antioxidants

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An alternative that achieves similar weight loss but with fewer gastrointestinal side effects or different tolerability characteristics may actually be preferable, even if the mechanism differs