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One placebo-controlled trial, called ATTAIN-MAINTAIN, followed adults who had previously completed the SURMOUNT-5 obesity trial, a randomized controlled study evaluating whether tirzepatide, the active ingredient in Zepbound, led to greater body weight reduction versus semaglutide in adults with obesity

These modications, along with no washing steps, have greatly simplied the ORAC assay

GLP-1 agonists, like the aforementioned liraglutide and semaglutide, appear to be some of the most effective medications

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Step six: manage the approval window Approved prior authorizations typically have a defined duration often one year, sometimes shorter