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These data in both male and female obese mice uncovered a critical role of protease-selective PAR2 activation in the regulation of DIO and postprandial GIP release in obesity

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Park SY, Bae JS, Cha EJ, Chu HH, Sohn JS, Moon WS

Although a decreasing trend in body weight and BMI was observed, GTE did not significantly reduce body weight and BMI of diabetic subjects (BMI around 26) in our study