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(2004, Annals of the New York Academy of Sciences) showed that T4 and its derived fragments greatly upregulate VEGF (vascular endothelial growth factor) expression in endothelial cells, promote endothelial tube formation in Matrigel assays, and reduce ischemic tissue loss in cardiac injury models

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Lab Chip 7 , 16601662 (2007)

A ketogenic diet modifies glutamate, gamma-aminobutyric acid and agmatine levels in the hippocampus of rats: a microdialysis study

Used for type 2 diabetes, this is known to block B12 absorption and the MHRA (Medicines and Healthcare Products Regulatory Agency) suggests that the B12 levels of metformin users should be monitored if they develop deficiency symptoms