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Characteristics of the included studies In total, 20 studies were selected after meeting the inclusion criteria, including ten animal studies and nine human studies

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However, test-tube and animal studies show that guarana extract may boost metabolism and limit fat cell production by suppressing certain genes ( Side effects: Because guarana is high in caffeine, it may cause insomnia, headaches, nervousness and increased heart rate and anxiety, especially when taken in high doses ( Summary Guarana which is especially high in caffeine may boost metabolism, but more research is needed to determine whether it suppresses appetite or promotes weight loss

Zinc is important for normal growth, wound healing, and sexual maturation