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Conversely, Intestinal epithelial cells can generate APRIL and BAFF in response to some probiotics or their metabolites, which causes B-cell class flipping to IgA-secreting plasma cells ( Figure 2 ) (139, 142)

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Its most robust research is in healing the GI tract

It acts as a master biological signal for tissue repair and regeneration, with particular potency in skin stimulating collagen and elastin production, activating antioxidant defenses, and remodeling damaged tissue

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