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1 Introduction Immune checkpoint inhibitors (ICIs) have become a major therapeutic advance in oncology over the past decade, markedly reshaping the management of multiple malignancies ( The FAERS is one of the largest global databases for adverse event reporting and represents a key resource for post-marketing safety surveillance and pharmacovigilance research

Higher gut pH induces the expression of tryptophanase (124)

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Hyalinosis and Ym1/Ym2 gene expression in the stomach and respiratory tract of 129S4/SvJae and wild-type and CYP1A2-null B6, 129 mice