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Immunotherapy should be held and potentially stopped should a patient experience a grade 2 or higher neurological irAE

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Retratrutide has shown even greater percentage weight loss than other medications in this category and may be an option for those few who did not fully respond or have plateaued on their weight loss from other medications

Back-propagating APs enhance NMDAR-mediated calcium signals in SST-positive and PV-positive interneurons from L2/3 of the visual cortex (Kaiser et al., 1997

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