The review also covered three therapeutic research strategies: direct GSH depletion (leading to ferroptosis or enhanced chemotherapy sensitivity), indirect approaches targeting the tumour microenvironment, and prodrug strategies utilising elevated tumour GSH for drug activation
Rather, they form a self-amplifying positive feedback loop orchestrated by the COF platform: an improved immune environment enhances treatment efficacy, and stronger therapeutic effects release more immune stimuli
Bn cnh , c nhiu pht hin ch ra glutathione c nh hng trc tip n qu trnh sn sinh sc t da, melanin
J Alzheimers Dis 66:517532 Matsuzawa D, Obata T, Shirayama Y, Nonaka H, Kanazawa Y, Yoshitome E, Takanashi J, Matsuda T, Shimizu E, Ikehira H, Iyo M, Hashimoto K (2008) Negative correlation between brain glutathione level and negative symptoms in schizophrenia: a 3T 1H-MRS study
Using the drug affinity response target stability technique, it was possible to observe that ASCT2 was protected from protein hydrolysis in a V-9302 concentration-dependent manner
