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Given the progressive nature of the disorder, disease pathogenesis is mainly triggered by continual processes such as geometric accumulation of oxidative radicals brought about by cellular inclusions and mitochondrial dysfunction 8,9,10

Rounding into 2023, it was increasingly clear that GLP-1s were not only highly effective medications, but highly charismatic products with broad consumer appeal

cmh-2022-0330-Supplementary-8.pdf Supplementary Material 9

Warning signs of intramuscular injection damage include redness, increased swelling, fever, and warmth of the skin at the injection site

While these medications show favorable outcomes in HbA1c reduction and weight loss, cost and tolerability remain significant barriers to widespread use