efectos secundarios de semaglutide Cuánto tiempo tarda en hacer efecto la semaglutida: plazos y factores Efectos adversos de Wegovy: todo

Modeling Parkinsons disease with the alpha-synuclein protein

GalvanoFLi VoltiGMalaguarneraMAvitabileTAnticTVacanteMet al

The following antibodies were used: anti-GPX4 (1:2000, Abcam, ab125066), anti-ACSL4 (1:1000, Abcam, ab155282), anti-TfR (1:1000, Invitrogen, H68.4), anti-FPN1 (1:1000, Eurogentec, Lege, Belgium) anti-ferritin (1:1000, Sigma, F5012), anti-phospho-NF-B p65 (1:1000, Cell Signalling Technology, 3039), anti-NF-B p65 (1:1000, Cell Signalling Technology, 8242), with anti-GAPDH (1:2000, Cell Signalling Technology, 2118) or anti--actin (1:2000, Sigma, A2066 and Abcam, ab49900) as loading control

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It is a 31-amino-acid linear peptide engineered with targeted substitutions and a C18 fatty diacid side chain conjugated to the -amino group of Lys26 , a modification studied for its role in enhancing metabolic stability and prolonging systemic persistence in research models