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4.2 GSH/GSSG Imbalance in Aging and Neurodegenerative Disease Because the brain has high energy demand, abundant oxidizable lipids, and strong dependence on mitochondrial function, glutathione metabolism is frequently studied in aging and neurodegeneration

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The agency flagged three adverse events in its FAERS database tied to compounded injectable BPC-157, including a case in which a patient developed diffuse hyperpigmentation and gingival darkening after using a blended BPC-157/TB-500 product labeled "research purposes only." The safety concern most specific to BPC-157 is its mechanism of action