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Side effects appear to be infrequent and mild in most reported cases, and may include: Temporary injection site reactions (with subcutaneous administration) Mild headache in some individuals Vivid dreams often considered a sign of enhanced REM sleep activity Occasional mild gastrointestinal discomfort DSIP does not appear to suppress respiratory function or cause the cognitive impairment sometimes associated with sedative-hypnotic drugs

1 : 88100 Cullis PR, DeKruijff B

[DOI] [PMC free article] [PubMed] [Google Scholar] Hou X.-N

Immunohistochemistry verified that estrogen signaling inhibits intestinal inflammation