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Because BPC 157 is based on a peptide fragment found in gastric juice, it has been studied for protective effects on the stomach and intestinal lining in preclinical models

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(2010) utilized IGF-1 and its analogs to investigate the relative contributions of PI3K/Akt versus MAPK/ERK signaling in IGF-1R-mediated cellular responses, demonstrating context-dependent pathway utilization across different cell types