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Body composition assessments, including imaging techniques such as dual-energy X-ray absorptiometry (DXA), have been used in clinical studies to analyze changes in adipose tissue, lean mass, and regional fat distribution following exposure to tri-agonist signaling compounds [2][3]

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13,15 Although we did not specifically evaluate patients for ECOG performance status, patients were generally similar in performance status to meet the VA criteria to receive checkpoint inhibitors