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However, the pharmacokinetic parameters after repeated IM administration changed slightly compared to those observed after a single IM injection, with a small decrease in C max and t 1/2 and an increase in T max

It contributes to red blood cell formation, nerve function, and DNA synthesis, making it indispensable for overall health

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In the UK, B12 replacement is typically administered via intramuscular hydroxocobalamin injections for patients with confirmed deficiency, particularly those with malabsorption or pernicious anaemia, as specified in the BNF and NICE CKS guidance on B12 and folate deficiency anaemia

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