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Because the liver stores several years' worth of B12, symptoms often creep in gradually, which is one reason the condition is underdiagnosed

For subcutaneous tirzepatide injections in the thigh, the optimal range is 27-30 gauge

Foot Ankle Clin 12:553567 Hsieh MJ, Liu HT, Wang CN, Huang HY, Lin Y, Ko YS, Wang JS, Chang VH, Pang JH (2017) Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation

So when I prescribe 1000 mcg daily, I am giving a large dose knowing that the absorption fraction is small

Fortunately, the post-bariatric periodic screenings that every patient will undergo is finely tuned to address both B12 and other vitamin deficiencies