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That oxidation happens inside mitochondria through beta-oxidation and the citric acid cycle, both of which require NAD+ as an electron acceptor

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These reactions were observed in clinical trials: Abdominal distension Abdominal pain Acute gallbladder disease Acute kidney injury Acute pancreatitis Allergic reactions Constipation Diarrhea Dizziness Dyspepsia (indigestion) Eructation (burping) Fatigue Flatulence Gastroenteritis Gastroesophageal reflux disease Headache Hypoglycemia (in diabetic patients) Nasopharyngitis (cold) Nausea Thyroid C-cell tumors Vomiting Studies, consumer reports and lawsuits have highlighted other side effects of semaglutide medications

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Be Cognizant of Reproductive and Hormonal Influences Breastfeeding There is strong evidence that breastfeeding decreases the risk of breast cancer in the mother (128)