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It comprises two GLP-1 analog chains linked to an Fc fragment of IgG4 (not the full antibody, just the Fc), making a large molecule (~63 kDa)

doi: 10.1080/10408398.2019.1688250 89 NapolitanoA.MillerS.NichollsA

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6,15,16 Taken together, the appropriate length is between C16 and C20 and most suitable lipidation position can be chosen from the following range of positions (starting from position 1): 10, 16, 20, 21, 28, and C-terminal

By building on the structure of ipamorelin, the researchers designed and synthesized a novel series of peptides that exhibit significantly enhanced potency and selectivity in stimulating growth hormone release