Studies using GCS inhibitors in multiple different animal models of PKD have demonstrated that reducing the production of GSLs can slow cyst growth and preserve kidney function
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[8] [9] Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation, which typically diminish over time with dose titration
After that, a melting curve analysis was performed with the following steps: 95 C for 15 s, 60 C for 60 s, and 95 C for 15 s
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