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Animal Model:Male Sprague-Dawley rats weighing 300 to 350 g with maintained plasma glucose concentration at 11 mM [2]

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We show that accumulated mutant-p53 protein suppresses the expression of SLC7A11 , a component of the cystine/glutamate antiporter, system x C , through binding to the master antioxidant transcription factor NRF2

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"I don't know how they're going to put the genie back in the bottle," Lee told AFP