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TB-500 (a Thymosin Beta-4 fragment) acts as a G-actin sequestering peptide affecting cytoskeletal remodelling and cell migration, with effects measured at the actin polymerization level rather than at receptor-pathway level

Naurath, H

FN receptors are located in every tissue that originates from the three primary germ layers and are therefore considered to modulate embryogenic cellular migration and anchoring (24), which suggested the FN signaling may mediate the cellular-ECM signal transduction that may, in turn, modulate LOX secretion

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