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This revealed that GHK-Cu influences 31.2% of all human genes at a threshold of 50% expression change an extraordinarily broad biological effect for a single molecule

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The secondary metabolite dose-dependently reduced the NF-B reporter gene expression that was stimulated by TNF- or LPS

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For the luciferase assay, HEK293T cells were seeded in 24-well plates until they reached 70% confluency and, subsequently, allocated into five groups: (1) transfected with GL-vector and Flag, (2) transfected with GL-VEGFA-WT and Flag-STAT6, (3) transfected with GL-VEGFA-Mut and Flag-STAT6, (4) transfected with GL-IL8-WT and Flag-STAT6, and (5) transfected with GL-IL8-Mut and Flag-STAT6