dpp-4 inhibitor and glp-1 receptor agonist combination not recommended ada Frontiers Current Insights, Advantages and Challenges

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Preclinical models help researchers ask mechanistic questions, but they do not automatically predict human outcomes

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Specifically, semaglutide achieved NASH resolution in up to 59% of patients at the 0.4 mg dosage, while liraglutide showed resolution in 39% of treated individuals compared to merely 9% with placebo