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It works by mimicking a naturally occurring hormone that helps regulate appetite, digestion, and blood sugar levels

The difference may partly reflect dose equivalency issues in trials rather than a true pharmacological difference

These include structured lifestyle interventions and behavioural support through NHS Tier 3 weight management services (information available at nhs.uk), as well as licensed pharmacological treatments where clinically appropriate including orlistat, semaglutide (Wegovy, subject to NICE Technology Appraisal TA875), and tirzepatide (Mounjaro, subject to NICE Technology Appraisal TA1026)

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Additionally, lithium, valproate, and carbamazepine showed neuroprotective effects, preventing reductions in synaptic protein levels induced by cytotoxicity