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The oral route means the medication passes through the GI tract rather than being injected subcutaneously, which could alter the pharmacokinetic profile and potentially influence which side effects are more or less prominent

The estimated background risk of major birth defects and miscarriage for the indicated population is increased when compared to the general population

Retatrutide shows none of these characteristics

Tirzepatide 5mg is indicated for adults diagnosed with type 2 diabetes mellitus as an adjunct to diet and exercise