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Furthermore, this study reported that mice exposed to three days of dLAN post MCAO increased TNF-, IL-6, and IL-1 in the ipsilateral hemisphere of the brain, and displayed increased anxiety-like behavior compared to control mice (Weil et al., 2020)

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Pre-treatment with topical anesthesia may be required as well

Moreover, a study of 87 young and middle-aged adults [36], as well as another study of 355 healthy young female students [37], found a positive association between VitB12 and sleep, with higher dietary intake of VitB12 associated with better sleep

[Revised in November 2018] [Accessed on 4th November 2022] 8